Coding
Part:BBa_K863015:Design
Designed by: Isabel Huber Group: iGEM12_Bielefeld-Germany (2012-09-20)
xccl laccase from Xanthomonas campestris with T7 promoter, RBS and His-tag
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal PstI site found at 196
Illegal PstI site found at 1582 - 12INCOMPATIBLE WITH RFC[12]Illegal PstI site found at 196
Illegal PstI site found at 1582 - 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 1131
- 23INCOMPATIBLE WITH RFC[23]Illegal PstI site found at 196
Illegal PstI site found at 1582 - 25INCOMPATIBLE WITH RFC[25]Illegal PstI site found at 196
Illegal PstI site found at 1582
Illegal NgoMIV site found at 267
Illegal NgoMIV site found at 372
Illegal NgoMIV site found at 623
Illegal NgoMIV site found at 816
Illegal NgoMIV site found at 820
Illegal NgoMIV site found at 1206
Illegal NgoMIV site found at 1227
Illegal AgeI site found at 554 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
Primers for isolation of the gene out of genomic DNA with BioBrick Prefix, pT7 promoter and RBS in the fwd primer and Suffix and His-tag in the rev primer.
fwd: 5'-ACGTGAATTCGCGGCCGCTTCTAGAGtaatacgactcactatagggagagaggagaaaaATGTCATTCGATCCCTTGTC-3'
rev: 5'-ACGTCTGCAGCGGCCGCTACTAGTATTATTAGTGATGGTGATGGTGATGTGCCTCCACCCGCACTT-3'
Source
The gene sequence was isolated from Xanthomonas campestris pv. campestris B100.
References
Hsiao, Y. M., Y. F. Liu, et al. (2011). "Functional characterization of copA gene encoding multicopper oxidase in Xanthomonas campestris pv. campestris." J Agric Food Chem 59(17): 9290-9302.